Anti-CD123 scFv h(CD28-FcεRIγ) CART, pCDCAR1

"The vector of anti-CD123 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD123. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD123 antibody linked to CD28 transmembrane domain/ endodomain and FcεRIγ signaling domains. And the vector product was designed for the treatment of acute myeloid leukaemia (AML). https://www.creative-biolabs.com/car-t/pcdcar1-cd123-h-28%CE%B3-t-340.htm"