Anti-CD123 scFv h(CD8-CD3ζ) CART, pCDCAR1

"The vector of anti-CD123 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD123. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD123 antibody linked to CD8 hinge-transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of acute myeloid leukaemia (AML). https://www.creative-biolabs.com/car-t/pcdcar1-cd123-h-8%CE%B6-t-344.htm"