Methyl 4-chlorocinnamate

Other names: 2-Propenoic acid, 3- (4-chlorophenyl)-, methyl ester CAS No.: 7560-44-3 Molecular formula: C10H9ClO2 Molecular weight: 196.630 Molar mass: 196.029114 Melting point: 76-77°C Boiling point: 292.8±15.0 °C at 760 mmHg Flash point: 144.4±15.8 °C Refractive index: 1.572 Properties : White Crystalline Powder, it can disolve in ethyl alcohol and diethyl ether, can't disolve in water. Purity : ≥99% Packaging : 25kg Paper barrel Storage method: Seal in a cool, dry environment. If used and stored according to specifications, it will not decompose. Usage : Methyl p-chlorocinnamate is an organic chemical, often used in industry, pharmaceutical industry, etc., obtained by reacting chlorobenzaldehyde with acetic anhydride. The chlorobenzene formaldehyde, acetic anhydride and sodium acetate with reaction 13 h under 180 ℃. After the reaction, it is slightly cold. Pour into the water, filter and wash the filter cake with water. Dissolve the cake repeatedly with ammonia until only a small amount of brownish-yellow sticky remains remain. The ammonium salt solution was filtered, then the chlorocinnamic acid was precipitated out with 3N dilute sulfuric acid, and the product was filtered and dried. Methyl p-chlorocinnamate is mainly used to synthesize methyl bromomethyl cinnamate from the upstream raw material of the antithrombotic agent ozagrel sodium. The methyl methylanilate was prepared by N- butyl diimide bromide bromide and the total yield was 67%.