Hydrochlorothiazide 58-93-5 [email protected]

high quality CAS 58-93-5 Hydrochlorothiazide Hydrochlorothiazide.jpg Hydrochlorothiazide (2).jpg Product Name: Hydrochlorothiazide Synonyms: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide;2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-,1,1-dioxide;3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide;6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide;6-Chloro-3,4-dihydro-7-sulphamoyl-1,2,4-ben-zoth-iadi-azine1,1-dioxcide;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine;6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxide CAS: 58-93-5 MF: C7H8ClN3O4S2 MW: 297.74 EINECS: 200-403-3 Hydrochlorothiazide (3).jpg Hydrochlorothiazide (2).jpg Hydrochlorothiazide (5).jpg Contents Specification Results Characteristics White or almost white Crystalline powder Complies Identification A: as per infrared absorption B: as per ultraviolet absorption Complies Solubility Very slightly soluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides. Complies Chloride ≤ 0.035% Complies Selenium < 0.003%max Complies Related Substances a) Any peak b) Sum of peak ≤0.5% ≤0.9% ≤0.04% ≤0.44% Heavy metal < 0.001%max Complies Residue on ignition ≤0.1% 0.034% 4-Amino-6-chloro-1.3- -Benzenedisulfonamide < 1% max 0.36% Loss on drying ≤ 0.5% 0.14% Organic volatile impurities Meets the requirements Complies Assay 98.0-102.0%(on the dried basis sub) 99.77% Conclusion: It complies with the requirements of the USP32 Hydrochlorothiazide (4).jpg 1.Edema disease: discharge excessive sodium and water body, reduce the extracellular fluid volume, eliminate edema.Common including congestive heart failure, liver cirrhosis ascites, nephrotic syndrome, acute or chronic nephritis edema, chronic renal failure caused by early, adrenal cortical hormone, and estrogen therapy of sodium and water retention. 2. High blood pressure, can be used alone or with other antihypertensive agents, mainly used in the treatment of essential hypertension. 3. Central or kidney diabetes insipidus. 4. Kidney stone disease: mainly used for the prevention of calcium salt composition form of stone. 5. also can be used to remove urinary tract infection caused by urinary frequency, urgency, urine pain symptoms