Metronidazole 443-48-1 [email protected]

Product Description Metronidazole is an antibiotic that is used commonly to treat protozoal infections and anaerobic bacterial infections. It also has anti-inflammatory effects in the bowel. Metronidazole is bactericidal; it kills bacterial microorganisms by disrupting their DNA. It is absorbed rapidly from the GI tract, metabolized by the liver and excreted in the urine and the feces. Because metronidazole only has activity against anaerobic bacteria, it is used commonly with other antibiotics when it is used to treat mixed-bacterial infections. It is compatible with many other antibiotics including penicillin antibiotics, aminoglycosides, and some cephalosporins. Certification of Analysis APPEARANCE A WHITE OR YELLOWISH CRYSTALLINE POWDER COMPLY SOLUBILITY SLIGHTLY SOLUBLE IN WATER,IN ACETONE,IN ALCOHOL AND IN METHYLENE CHLOROFORM,VERY SLIGHTLY SOLUBLE IN ETHER COMPLY IDENTIFICATION A),B) C) INFRARED a) MELTING POINT 159-163°C b) SPECIFIC ABSORBANCE 365-389 A) 160.1-160.5°C B) 377 LOSS ON DRYING 0.5% MAX 0.15% SULPHATE ASHES 0.1% MAX 0.07% HEAVY METAL 20PPM MAX LESS THAN 20PPM RESIDUAL SOLVENTS ETHANEDIOL LESS THAN 620PPM LESS THAN 620PPM PARTICLE SIZE 40-60MESH COMPLY APPEARANCE OF SOLUTION SUSPENSION 2 AND SOLUTION GY6 COMPLY RELATED SUBSTANCE 1) IMPURITY 0.1%MAX 0.06% 2)TOTAL IMPURITY 0.2%MAX 0.14% 3)DISREGARD LIMITED 0.01% MAX PASS ASSAY 99.0%-101.0% C6H9N3O3 99.62%C6H9N3O3 Function&Application Function Indications: for the treatment of intestinal and parenteral amebiasis (such as amoebic liver abscess, pleural amebiasis, etc.). but also for the treatment of vaginal trichomoniasis, coccidiosis pouch and cutaneous leishmaniasis, Guinea worm infection. is still widely used in the treatment of anaerobic infections.