TDot Performance
ON, CA
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SKU DXMIQ-10-101-140
Etelcalcetide
Velcalcetide; telcalcetide; AMG-416; KAI-4169; ONO-5163
Drugs & Pharmaceutical Chemicals
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Details
Etelcalcetide is used for the treatment of secondary hyperparathyroidism in patients withchronic kidney disease(CKD) on hemodialysis. Etelcalcetide is a calcimimetic agent that allosterically modulates the calcium-sensing receptor (CaSR). Etelcalcetide binds to the CaSR and enhances activation of the receptor by extracellular calcium. Activation of the CaSR on parathyroid chief cells decreases PTH secretion.
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