TDot Performance
ON, CA
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SKU DXMIQ-123948-87-8
Topotecan Hydrochloride
TPT; SKF-104864A; SKFS-104864-A; 9-[(Dimethylamino)methyl]-10-hydroxy-(20S)-camp
Drugs & Pharmaceutical Chemicals
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Details
Topotecan Hydrochloride is the water-soluble hydrochloride salt preparation of Topotecan, a potent inhibitor of topoisomerase 1, and an apoptosis inducer, producing proapoptotic and antiproliferative effects. Topotecan is a semisynthetic derivative of the natural product alkaloid camptothecin. It is described to stabilize topoisomerase I/DNA cleavable complexes and promote rapid apoptotic cell death in radiation-resistant human B-lineage acute lymphoblastic leukemia cells.http://www.creative-peptides.com/product/topotecan-hydrochloride-item-10-101-124-112.html