AGRP/Agouti-related protein peptide

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. https://www.creative-diagnostics.com/AGRP-Agouti-related-protein-peptide-178578-436.htm