Recombinant Human CD4 Protein(His tag)

Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1 (PubMed:2214026, PubMed:16331979, PubMed:9641677). Down-regulated by HIV-1 Vpu (PubMed:17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed:7909607). Recombinant Human CD4 Protein (P01730) (Lys 26 - Trp 390) with a polyhistidine tag at the C-terminus was expressed in HEK293. https://www.profacgen.com/rhuman-cd4-his-tag-1340.htm